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HIV Pol Inhibits HIV Budding and Mediates the Severe Budding Defect of Gag-Pol

The prevailing hypothesis of HIV budding posits that the viral Gag protein drives budding, and that the Gag p6 peptide plays an essential role by recruiting host-cell budding factors to sites of HIV assembly. HIV also expresses a second Gag protein, p160 Gag-Pol, which lacks p6 and fails to bud from...

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Detalles Bibliográficos
Autores principales: Gan, Xin, Gould, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250436/
https://www.ncbi.nlm.nih.gov/pubmed/22235295
http://dx.doi.org/10.1371/journal.pone.0029421