Pharmacological Inhibition of Caspase and Calpain Proteases: A Novel Strategy to Enhance the Homing Responses of Cord Blood HSPCs during Expansion

BACKGROUND: Expansion of hematopoietic stem/progenitor cells (HSPCs) is a well-known strategy employed to facilitate the transplantation outcome. We have previously shown that the prevention of apoptosis by the inhibition of cysteine proteases, caspase and calpain played an important role in the exp...

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Detalles Bibliográficos
Autores principales: V. M., Sangeetha, Kadekar, Darshana, Kale, Vaijayanti P., Limaye, Lalita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250442/
https://www.ncbi.nlm.nih.gov/pubmed/22235291
http://dx.doi.org/10.1371/journal.pone.0029383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250442/
https://www.ncbi.nlm.nih.gov/pubmed/22235291
http://dx.doi.org/10.1371/journal.pone.0029383

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