siRNA Silencing of Proteasome Maturation Protein (POMP) Activates the Unfolded Protein Response and Constitutes a Model for KLICK Genodermatosis

Keratosis linearis with ichthyosis congenita and keratoderma (KLICK) is an autosomal recessive skin disorder associated with a single-nucleotide deletion in the 5′untranslated region of the proteasome maturation protein (POMP) gene. The deletion causes a relative switch in transcription start sites...

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Detalles Bibliográficos
Autores principales: Dahlqvist, Johanna, Törmä, Hans, Badhai, Jitendra, Dahl, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250448/
https://www.ncbi.nlm.nih.gov/pubmed/22235297
http://dx.doi.org/10.1371/journal.pone.0029471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250448/
https://www.ncbi.nlm.nih.gov/pubmed/22235297
http://dx.doi.org/10.1371/journal.pone.0029471

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