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siRNA Silencing of Proteasome Maturation Protein (POMP) Activates the Unfolded Protein Response and Constitutes a Model for KLICK Genodermatosis

Keratosis linearis with ichthyosis congenita and keratoderma (KLICK) is an autosomal recessive skin disorder associated with a single-nucleotide deletion in the 5′untranslated region of the proteasome maturation protein (POMP) gene. The deletion causes a relative switch in transcription start sites...

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Detalles Bibliográficos
Autores principales:	Dahlqvist, Johanna, Törmä, Hans, Badhai, Jitendra, Dahl, Niklas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250448/ https://www.ncbi.nlm.nih.gov/pubmed/22235297 http://dx.doi.org/10.1371/journal.pone.0029471

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