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The Transmembrane Domain of CEACAM1-4S Is a Determinant of Anchorage Independent Growth and Tumorigenicity

CEACAM1 is a multifunctional Ig-like cell adhesion molecule expressed by epithelial cells in many organs. CEACAM1-4L and CEACAM1-4S, two isoforms produced by differential splicing, are predominant in rat liver. Previous work has shown that downregulation of both isoforms occurs in rat hepatocellular...

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Detalles Bibliográficos
Autores principales: Lawson, Erica L., Mills, David R., Brilliant, Kate E., Hixson, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250453/
https://www.ncbi.nlm.nih.gov/pubmed/22235309
http://dx.doi.org/10.1371/journal.pone.0029606