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Reproducibility and Concordance of Differential DNA Methylation and Gene Expression in Cancer

BACKGROUND: Hundreds of genes with differential DNA methylation of promoters have been identified for various cancers. However, the reproducibility of differential DNA methylation discoveries for cancer and the relationship between DNA methylation and aberrant gene expression have not been systemati...

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Detalles Bibliográficos
Autores principales: Yao, Chen, Li, Hongdong, Shen, Xiaopei, He, Zheng, He, Lang, Guo, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250460/
https://www.ncbi.nlm.nih.gov/pubmed/22235325
http://dx.doi.org/10.1371/journal.pone.0029686