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The S. pombe Histone H2A Dioxygenase Ofd2 Regulates Gene Expression during Hypoxia

Post-translational modification of histone proteins are known to play an important role in regulating chromatin structure. In an effort to find additional histone modifications we set out to screen enzymes of the 2-oxoglutarate and Fe(II)-dependent (2-OG-Fe(II)) dioxygenase family for activity towar...

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Detalles Bibliográficos
Autores principales: Lando, David, Balmer, Jenny, Laue, Ernest D., Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250473/
https://www.ncbi.nlm.nih.gov/pubmed/22235339
http://dx.doi.org/10.1371/journal.pone.0029765