Impaired CK1 Delta Activity Attenuates SV40-Induced Cellular Transformation In Vitro and Mouse Mammary Carcinogenesis In Vivo

Simian virus 40 (SV40) is a powerful tool to study cellular transformation in vitro, as well as tumor development and progression in vivo. Various cellular kinases, among them members of the CK1 family, play an important role in modulating the transforming activity of SV40, including the transformin...

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Detalles Bibliográficos
Autores principales: Hirner, Heidrun, Günes, Cagatay, Bischof, Joachim, Wolff, Sonja, Grothey, Arnhild, Kühl, Marion, Oswald, Franz, Wegwitz, Florian, Bösl, Michael R., Trauzold, Anna, Henne-Bruns, Doris, Peifer, Christian, Leithäuser, Frank, Deppert, Wolfgang, Knippschild, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250488/
https://www.ncbi.nlm.nih.gov/pubmed/22235331
http://dx.doi.org/10.1371/journal.pone.0029709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250488/
https://www.ncbi.nlm.nih.gov/pubmed/22235331
http://dx.doi.org/10.1371/journal.pone.0029709

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