Hu.4-1BB-Fc fusion protein inhibits allergic inflammation and airway hyperresponsiveness in a murine model of asthma

PURPOSE: 4-1BB (CD 137) is a costimulatory molecule expressed on activated T-cells. Repression by 4-1BB is thought to attenuate Th2-mediated allergic reactions. The aim of this study was to investigate the effect of 4-1BB on allergic airway inflammation in a murine asthma model. METHODS: BALB/c mice...

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Detalles Bibliográficos
Autores principales: Kim, Byoung-Ju, Kwon, Ji-Won, Seo, Ju-Hee, Choi, Won-Ah, Kim, Young-Jun, Kang, Mi-Jin, Yu, Jinho, Hong, Soo-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pediatric Society 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250603/
https://www.ncbi.nlm.nih.gov/pubmed/22232630
http://dx.doi.org/10.3345/kjp.2011.54.9.373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250603/
https://www.ncbi.nlm.nih.gov/pubmed/22232630
http://dx.doi.org/10.3345/kjp.2011.54.9.373

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