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Modeling the Autonomic and Metabolic Effects of Obstructive Sleep Apnea: A Simulation Study
Long-term exposure to intermittent hypoxia and sleep fragmentation introduced by recurring obstructive sleep apnea (OSA) has been linked to subsequent cardiovascular disease and Type 2 diabetes. The underlying mechanisms remain unclear, but impairment of the normal interactions among the systems tha...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250672/ https://www.ncbi.nlm.nih.gov/pubmed/22291654 http://dx.doi.org/10.3389/fphys.2011.00111 |