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Novel dimeric DOTA-coupled peptidic Y(1)-receptor antagonists for targeting of neuropeptide Y receptor-expressing cancers

BACKGROUND: Several peptide hormone receptors were identified that are specifically over-expressed on the cell surface of certain human tumors. For example, high incidence and density of the Y(1 )subtype of neuropeptide Y (NPY) receptors are found in breast tumors. Recently, we demonstrated that the...

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Detalles Bibliográficos
Autores principales: Chatenet, David, Cescato, Renzo, Waser, Beatrice, Erchegyi, Judit, Rivier, Jean E, Reubi, Jean Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250963/
https://www.ncbi.nlm.nih.gov/pubmed/22214201
http://dx.doi.org/10.1186/2191-219X-1-21