Experimental α-particle radioimmunotherapy of breast cancer using (227)Th-labeled p-benzyl-DOTA-trastuzumab

BACKGROUND: The aim of the present study was to explore the biodistribution, normal tissue toxicity, and therapeutic efficacy of the internalizing low-dose rate alpha-particle-emitting radioimmunoconjugate (227)Th-trastuzumab in mice with HER2-expressing breast cancer xenografts. METHODS: Biodistrib...

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Detalles Bibliográficos
Autores principales: Abbas, Nasir, Heyerdahl, Helen, Bruland, Øyvind S, Borrebæk, Jørgen, Nesland, Jahn, Dahle, Jostein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250964/
https://www.ncbi.nlm.nih.gov/pubmed/22214432
http://dx.doi.org/10.1186/2191-219X-1-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250964/
https://www.ncbi.nlm.nih.gov/pubmed/22214432
http://dx.doi.org/10.1186/2191-219X-1-18

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