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Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets

BACKGROUND: Photoimmunodetection, in which monoclonal antibodies [mAbs] are labeled with fluorescent dyes, might have clinical potential for early detection and characterization of cancer. For this purpose, the dye should be coupled in an inert way to mAb. In this study, different equivalents of IRD...

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Detalles Bibliográficos
Autores principales: Cohen, Ruth, Stammes, Marieke A, de Roos, Inge HC, Stigter-van Walsum, Marijke, Visser, Gerard WM, van Dongen, Guus AMS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250998/
https://www.ncbi.nlm.nih.gov/pubmed/22214225
http://dx.doi.org/10.1186/2191-219X-1-31