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Solulin reduces infarct volume and regulates gene-expression in transient middle cerebral artery occlusion in rats
BACKGROUND: Thrombolysis after acute ischemic stroke has only proven to be beneficial in a subset of patients. The soluble recombinant analogue of human thrombomodulin, Solulin, was studied in an in vivo rat model of acute ischemic stroke. METHODS: Male SD rats were subjected to 2 hrs of transient m...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251036/ https://www.ncbi.nlm.nih.gov/pubmed/22082476 http://dx.doi.org/10.1186/1471-2202-12-113 |