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Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

BACKGROUND: Sensitive antibody-based tumor targeting has the potential not only to image metastatic and micrometastatic disease, but also to be the basis of targeted therapy. The vast majority of pancreas cancers express carcinoembryonic antigen (CEA). Thus, we sought to evaluate the potential of CE...

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Detalles Bibliográficos
Autores principales: Girgis, Mark D, Olafsen, Tove, Kenanova, Vania, McCabe, Katelyn E, Wu, Anna M, Tomlinson, James S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251041/
https://www.ncbi.nlm.nih.gov/pubmed/22214289
http://dx.doi.org/10.1186/2191-219X-1-24