Cargando…
Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment
BACKGROUND: Sensitive antibody-based tumor targeting has the potential not only to image metastatic and micrometastatic disease, but also to be the basis of targeted therapy. The vast majority of pancreas cancers express carcinoembryonic antigen (CEA). Thus, we sought to evaluate the potential of CE...
Autores principales: | Girgis, Mark D, Olafsen, Tove, Kenanova, Vania, McCabe, Katelyn E, Wu, Anna M, Tomlinson, James S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251041/ https://www.ncbi.nlm.nih.gov/pubmed/22214289 http://dx.doi.org/10.1186/2191-219X-1-24 |
Ejemplares similares
-
CA19-9 as a Potential Target for Radiolabeled Antibody-Based Positron Emission Tomography of Pancreas Cancer
por: Girgis, Mark D., et al.
Publicado: (2011) -
Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells
por: Hutt, Meike, et al.
Publicado: (2018) -
Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E
por: Miethe, Sebastian, et al.
Publicado: (2015) -
Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein
por: Pavoni, Emiliano, et al.
Publicado: (2006) -
Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma
por: Zhang, Chengcheng, et al.
Publicado: (2023)