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Failure of annexin-based apoptosis imaging in the assessment of antiangiogenic therapy effects

BACKGROUND: Molecular apoptosis imaging is frequently discussed to be useful for monitoring cancer therapy. We demonstrate that the sole assessment of therapy effects by apoptosis imaging can be misleading, depending on the therapy effect on the tumor vasculature. METHODS: Apoptosis was investigated...

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Detalles Bibliográficos
Autores principales: Lederle, Wiltrud, Arns, Susanne, Rix, Anne, Gremse, Felix, Doleschel, Dennis, Schmaljohann, Jörn, Mottaghy, Felix M, Kiessling, Fabian, Palmowski, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251208/
https://www.ncbi.nlm.nih.gov/pubmed/22214377
http://dx.doi.org/10.1186/2191-219X-1-26