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Mini-PEG spacering of VAP-1-targeting (68)Ga-DOTAVAP-P1 peptide improves PET imaging of inflammation

BACKGROUND: Vascular adhesion protein-1 (VAP-1) is an adhesion molecule that plays a key role in recruiting leucocytes into sites of inflammation. We have previously shown that (68)Gallium-labelled VAP-1-targeting peptide ((68)Ga-DOTAVAP-P1) is a positron emission tomography (PET) imaging agent, cap...

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Detalles Bibliográficos
Autores principales: Autio, Anu, Henttinen, Tiina, Sipilä, Henri J, Jalkanen, Sirpa, Roivainen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251254/
https://www.ncbi.nlm.nih.gov/pubmed/22214508
http://dx.doi.org/10.1186/2191-219X-1-10