Long-term effects of high-fat or high-carbohydrate diets on glucose tolerance in mice with heterozygous carnitine palmitoyltransferase-1a deficiency

Background: Abnormal fatty acid metabolism is an important feature in the mechanisms of insulin resistance and β-cell dysfunction. Carnitine palmitoyltransferase-1a (CPT-1a, liver isoform) has a pivotal role in the regulation of mitochondrial fatty acid oxidation. We investigated the role of CPT-1a...

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Detalles Bibliográficos
Autores principales: Nyman, L R, Tian, L, Hamm, D A, Schoeb, T R, Gower, B A, Nagy, T R, Wood, P A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251273/
https://www.ncbi.nlm.nih.gov/pubmed/22229081
http://dx.doi.org/10.1038/nutd.2011.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251273/
https://www.ncbi.nlm.nih.gov/pubmed/22229081
http://dx.doi.org/10.1038/nutd.2011.11

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