Cardiac-Oxidized Antigens Are Targets of Immune Recognition by Antibodies and Potential Molecular Determinants in Chagas Disease Pathogenesis

Trypanosoma cruzi elicits reactive oxygen species (ROS) of inflammatory and mitochondrial origin in infected hosts. In this study, we examined ROS-induced oxidative modifications in the heart and determined whether the resultant oxidized cardiac proteins are targets of immune response and of patholo...

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Detalles Bibliográficos
Autores principales: Dhiman, Monisha, Zago, Maria Paola, Nunez, Sonia, Amoroso, Alejandro, Rementeria, Hugo, Dousset, Pierre, Burgos, Federico Nunez, Garg, Nisha Jain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251564/
https://www.ncbi.nlm.nih.gov/pubmed/22238578
http://dx.doi.org/10.1371/journal.pone.0028449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251564/
https://www.ncbi.nlm.nih.gov/pubmed/22238578
http://dx.doi.org/10.1371/journal.pone.0028449

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