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Exposure to N-Ethyl-N-Nitrosourea in Adult Mice Alters Structural and Functional Integrity of Neurogenic Sites

BACKGROUND: Previous studies have shown that prenatal exposure to the mutagen N-ethyl-N-nitrosourea (ENU), a N-nitroso compound (NOC) found in the environment, disrupts developmental neurogenesis and alters memory formation. Previously, we showed that postnatal ENU treatment induced lasting deficits...

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Detalles Bibliográficos
Autores principales: Capilla-Gonzalez, Vivian, Gil-Perotin, Sara, Ferragud, Antonio, Bonet-Ponce, Luis, Canales, Juan Jose, Garcia-Verdugo, Jose Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251592/
https://www.ncbi.nlm.nih.gov/pubmed/22238669
http://dx.doi.org/10.1371/journal.pone.0029891