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CTL Responses of High Functional Avidity and Broad Variant Cross-Reactivity Are Associated with HIV Control

Cytotoxic T lymphocyte (CTL) responses targeting specific HIV proteins, in particular Gag, have been associated with relative control of viral replication in vivo. However, Gag-specific CTL can also be detected in individuals who do not control the virus and it remains thus unclear how Gag-specific...

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Detalles Bibliográficos
Autores principales: Mothe, Beatriz, Llano, Anuska, Ibarrondo, Javier, Zamarreño, Jennifer, Schiaulini, Mattia, Miranda, Cristina, Ruiz-Riol, Marta, Berger, Christoph T., Herrero, M. José, Palou, Eduard, Plana, Montse, Rolland, Morgane, Khatri, Ashok, Heckerman, David, Pereyra, Florencia, Walker, Bruce D., Weiner, David, Paredes, Roger, Clotet, Bonaventura, Felber, Barbara K., Pavlakis, George N., Mullins, James I., Brander, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251596/
https://www.ncbi.nlm.nih.gov/pubmed/22238642
http://dx.doi.org/10.1371/journal.pone.0029717