Natural Amyloid-Beta Oligomers Acutely Impair the Formation of a Contextual Fear Memory in Mice

Memory loss is one of the hallmark symptoms of Alzheimer's disease (AD). It has been proposed that soluble amyloid-beta (Abeta) oligomers acutely impair neuronal function and thereby memory. We here report that natural Abeta oligomers acutely impair contextual fear memory in mice. A natural Abe...

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Detalles Bibliográficos
Autores principales: Kittelberger, Kara A., Piazza, Fabrizio, Tesco, Giuseppina, Reijmers, Leon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251597/
https://www.ncbi.nlm.nih.gov/pubmed/22238679
http://dx.doi.org/10.1371/journal.pone.0029940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251597/
https://www.ncbi.nlm.nih.gov/pubmed/22238679
http://dx.doi.org/10.1371/journal.pone.0029940

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