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Natural Amyloid-Beta Oligomers Acutely Impair the Formation of a Contextual Fear Memory in Mice
Memory loss is one of the hallmark symptoms of Alzheimer's disease (AD). It has been proposed that soluble amyloid-beta (Abeta) oligomers acutely impair neuronal function and thereby memory. We here report that natural Abeta oligomers acutely impair contextual fear memory in mice. A natural Abe...
Autores principales: | Kittelberger, Kara A., Piazza, Fabrizio, Tesco, Giuseppina, Reijmers, Leon G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251597/ https://www.ncbi.nlm.nih.gov/pubmed/22238679 http://dx.doi.org/10.1371/journal.pone.0029940 |
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