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Intradermal Electroporation of Naked Replicon RNA Elicits Strong Immune Responses
RNA-based vaccines represent an interesting immunization modality, but suffer from poor stability and a lack of efficient and clinically feasible delivery technologies. This study evaluates the immunogenic potential of naked in vitro transcribed Semliki Forest virus replicon RNA (RREP) delivered int...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251598/ https://www.ncbi.nlm.nih.gov/pubmed/22238645 http://dx.doi.org/10.1371/journal.pone.0029732 |