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Intradermal Electroporation of Naked Replicon RNA Elicits Strong Immune Responses

RNA-based vaccines represent an interesting immunization modality, but suffer from poor stability and a lack of efficient and clinically feasible delivery technologies. This study evaluates the immunogenic potential of naked in vitro transcribed Semliki Forest virus replicon RNA (RREP) delivered int...

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Detalles Bibliográficos
Autores principales: Johansson, Daniel X., Ljungberg, Karl, Kakoulidou, Maria, Liljeström, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251598/
https://www.ncbi.nlm.nih.gov/pubmed/22238645
http://dx.doi.org/10.1371/journal.pone.0029732