Cargando…
Intradermal Electroporation of Naked Replicon RNA Elicits Strong Immune Responses
RNA-based vaccines represent an interesting immunization modality, but suffer from poor stability and a lack of efficient and clinically feasible delivery technologies. This study evaluates the immunogenic potential of naked in vitro transcribed Semliki Forest virus replicon RNA (RREP) delivered int...
Autores principales: | Johansson, Daniel X., Ljungberg, Karl, Kakoulidou, Maria, Liljeström, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251598/ https://www.ncbi.nlm.nih.gov/pubmed/22238645 http://dx.doi.org/10.1371/journal.pone.0029732 |
Ejemplares similares
-
The Adjuvant Activity of Alphavirus Replicons Is Enhanced by Incorporating the Microbial Molecule Flagellin into the Replicon
por: Knudsen, Maria L., et al.
Publicado: (2013) -
DNA-launched RNA replicon vaccines induce potent anti-Ebolavirus immune responses that can be further improved by a recombinant MVA boost
por: Öhlund, Pontus, et al.
Publicado: (2018) -
Alphavirus Replicon DNA Expressing HIV Antigens Is an Excellent Prime for Boosting with Recombinant Modified Vaccinia Ankara (MVA) or with HIV gp140 Protein Antigen
por: Knudsen, Maria L., et al.
Publicado: (2015) -
DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques
por: Kulkarni, Viraj, et al.
Publicado: (2014) -
Improving the Repeatability and Efficacy of Intradermal Electroporated Self-Replicating mRNA
por: Huysmans, Hanne, et al.
Publicado: (2019)