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Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins
Hsp27 belongs to the heat shock protein family and displays chaperone properties in stress conditions by holding unfolded polypeptides, hence avoiding their inclination to aggregate. Hsp27 is often referenced as an anti-cancer therapeutic target, but apart from its well-described ability to interfer...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251601/ https://www.ncbi.nlm.nih.gov/pubmed/22238643 http://dx.doi.org/10.1371/journal.pone.0029719 |