Disease-Associated Mutations Prevent GPR56-Collagen III Interaction

GPR56 is a member of the adhesion G protein-coupled receptor (GPCR) family. Mutations in GPR56 cause a devastating human brain malformation called bilateral frontoparietal polymicrogyria (BFPP). Using the N-terminal fragment of GPR56 (GPR56(N)) as a probe, we have recently demonstrated that collagen...

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Detalles Bibliográficos
Autores principales: Luo, Rong, Jin, Zhaohui, Deng, Yiyu, Strokes, Natalie, Piao, Xianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251603/
https://www.ncbi.nlm.nih.gov/pubmed/22238662
http://dx.doi.org/10.1371/journal.pone.0029818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251603/
https://www.ncbi.nlm.nih.gov/pubmed/22238662
http://dx.doi.org/10.1371/journal.pone.0029818

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