Pharmaceutical regulation of telomerase and its clinical potential

Telomeres serve the dual function of protecting chromosomes from genomic instability as well as protecting the ends of chromosomes from DNA damage machinery. The enzyme responsible for telomere maintenance is telomerase, an enzyme capable of reverse transcription. Telomerase activity is typically li...

Descripción completa

Detalles Bibliográficos
Autores principales: Sprouse, Alyssa A, Steding, Catherine E, Herbert, Brittney-Shea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251731/
https://www.ncbi.nlm.nih.gov/pubmed/21973217
http://dx.doi.org/10.1111/j.1582-4934.2011.01460.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251731/
https://www.ncbi.nlm.nih.gov/pubmed/21973217
http://dx.doi.org/10.1111/j.1582-4934.2011.01460.x

Ejemplares similares