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Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer
The use of trastuzumab, a monoclonal antibody that targets the human epidermal growth factor receptor 2 (HER2) alteration present in 25 to 30% of breast cancers, has been associated with improved survival outcomes in both the adjuvant and metastatic settings. However, despite the robust clinical eff...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251862/ https://www.ncbi.nlm.nih.gov/pubmed/22215104 http://dx.doi.org/10.1038/bjc.2011.516 |