Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

BACKGROUND: We have shown that a sodium ionophore monensin inhibits prostate cancer cell growth. A structurally related compound to monensin, salinomycin, was recently identified as a putative cancer stem cell inhibitor. METHODS: The growth inhibitory potential of salinomycin was studied in a panel...

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Detalles Bibliográficos
Autores principales: Ketola, K, Hilvo, M, Hyötyläinen, T, Vuoristo, A, Ruskeepää, A-L, Orešič, M, Kallioniemi, O, Iljin, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251868/
https://www.ncbi.nlm.nih.gov/pubmed/22215106
http://dx.doi.org/10.1038/bjc.2011.530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251868/
https://www.ncbi.nlm.nih.gov/pubmed/22215106
http://dx.doi.org/10.1038/bjc.2011.530

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