Enhancing the immunogenicity of tumour lysate-loaded dendritic cell vaccines by conjugation to virus-like particles

BACKGROUND: Tumour cell lysates are an excellent source of many defined and undefined tumour antigens and have been used clinically in immunotherapeutic regimes but with limited success. METHODS: We conjugated Mel888 melanoma lysates to rabbit haemorrhagic disease virus virus-like particles (VLP), w...

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Detalles Bibliográficos
Autores principales: Win, S J, McMillan, D G G, Errington-Mais, F, Ward, V K, Young, S L, Baird, M A, Melcher, A A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251873/
https://www.ncbi.nlm.nih.gov/pubmed/22134504
http://dx.doi.org/10.1038/bjc.2011.538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251873/
https://www.ncbi.nlm.nih.gov/pubmed/22134504
http://dx.doi.org/10.1038/bjc.2011.538

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