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Second Order Rate Constants of Donor-Strand Exchange Reveal Individual Amino Acid Residues Important in Determining the Subunit Specificity of Pilus Biogenesis

P pili are hair-like adhesive structures that are assembled on the outer membrane (OM) of uropathogenic Escherichia coli by the chaperone-usher pathway. In this pathway, chaperone-subunit complexes are formed in the periplasm and targeted to an OM assembly platform, the usher. Pilus subunits display...

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Detalles Bibliográficos
Autores principales: Leney, Aneika C., Phan, Gilles, Allen, William, Verger, Denis, Waksman, Gabriel, Radford, Sheena E., Ashcroft, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252035/
https://www.ncbi.nlm.nih.gov/pubmed/21953104
http://dx.doi.org/10.1007/s13361-011-0146-4