Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm

In mammalian cells, AU-rich elements (AREs) are well known regulatory sequences located in the 3′ untranslated region (UTR) of many short-lived mRNAs. AREs cause mRNAs to be degraded rapidly and thereby suppress gene expression at the posttranscriptional level. Based on the number of AUUUA pentamers...

Descripción completa

Detalles Bibliográficos
Autores principales: Spasic, Milan, Friedel, Caroline C., Schott, Johanna, Kreth, Jochen, Leppek, Kathrin, Hofmann, Sarah, Ozgur, Sevim, Stoecklin, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252268/
https://www.ncbi.nlm.nih.gov/pubmed/22242014
http://dx.doi.org/10.1371/journal.pgen.1002433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252268/
https://www.ncbi.nlm.nih.gov/pubmed/22242014
http://dx.doi.org/10.1371/journal.pgen.1002433

Ejemplares similares