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Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm

In mammalian cells, AU-rich elements (AREs) are well known regulatory sequences located in the 3′ untranslated region (UTR) of many short-lived mRNAs. AREs cause mRNAs to be degraded rapidly and thereby suppress gene expression at the posttranscriptional level. Based on the number of AUUUA pentamers...

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Detalles Bibliográficos
Autores principales:	Spasic, Milan, Friedel, Caroline C., Schott, Johanna, Kreth, Jochen, Leppek, Kathrin, Hofmann, Sarah, Ozgur, Sevim, Stoecklin, Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252268/ https://www.ncbi.nlm.nih.gov/pubmed/22242014 http://dx.doi.org/10.1371/journal.pgen.1002433

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