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Roles of quaternary structure and cysteine residues in the activity of human serine racemase

BACKGROUND: D-serine is an important coagonist at the NR1 subunit of the NMDA receptor class of glutamate receptors. It is chiefly synthesized in the CNS by serine racemase (SR). Regulation of SR activity is still poorly understood. As step toward developing reagents and methods for investigating SR...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Barger, Steven W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252284/
https://www.ncbi.nlm.nih.gov/pubmed/22151352
http://dx.doi.org/10.1186/1471-2091-12-63