Hydroxybenzothiazoles as New Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1)

17β-estradiol (E2), the most potent estrogen in humans, known to be involved in the development and progession of estrogen-dependent diseases (EDD) like breast cancer and endometriosis. 17β-HSD1, which catalyses the reduction of the weak estrogen estrone (E1) to E2, is often overexpressed in breast...

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Detalles Bibliográficos
Autores principales: Spadaro, Alessandro, Negri, Matthias, Marchais-Oberwinkler, Sandrine, Bey, Emmanuel, Frotscher, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252304/
https://www.ncbi.nlm.nih.gov/pubmed/22242164
http://dx.doi.org/10.1371/journal.pone.0029252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252304/
https://www.ncbi.nlm.nih.gov/pubmed/22242164
http://dx.doi.org/10.1371/journal.pone.0029252

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