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Hydroxybenzothiazoles as New Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1)

17β-estradiol (E2), the most potent estrogen in humans, known to be involved in the development and progession of estrogen-dependent diseases (EDD) like breast cancer and endometriosis. 17β-HSD1, which catalyses the reduction of the weak estrogen estrone (E1) to E2, is often overexpressed in breast...

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Detalles Bibliográficos
Autores principales:	Spadaro, Alessandro, Negri, Matthias, Marchais-Oberwinkler, Sandrine, Bey, Emmanuel, Frotscher, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252304/ https://www.ncbi.nlm.nih.gov/pubmed/22242164 http://dx.doi.org/10.1371/journal.pone.0029252

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