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Chemotherapy-induced cognitive impairment is associated with decreases in cell proliferation and histone modifications

BACKGROUND: In this study, we examined the effects of cyclophosphamide, methothrexate, and 5-Fluorouracil (CMF) drug combination on various aspects of learning and memory. We also examined the effects of CMF on cell proliferation and chromatin remodeling as possible underlying mechanisms to explain...

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Detalles Bibliográficos
Autores principales: Briones, Teresita L, Woods, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252305/
https://www.ncbi.nlm.nih.gov/pubmed/22152030
http://dx.doi.org/10.1186/1471-2202-12-124