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Chemotherapy-induced cognitive impairment is associated with decreases in cell proliferation and histone modifications
BACKGROUND: In this study, we examined the effects of cyclophosphamide, methothrexate, and 5-Fluorouracil (CMF) drug combination on various aspects of learning and memory. We also examined the effects of CMF on cell proliferation and chromatin remodeling as possible underlying mechanisms to explain...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252305/ https://www.ncbi.nlm.nih.gov/pubmed/22152030 http://dx.doi.org/10.1186/1471-2202-12-124 |