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Chemotherapy-induced cognitive impairment is associated with decreases in cell proliferation and histone modifications
BACKGROUND: In this study, we examined the effects of cyclophosphamide, methothrexate, and 5-Fluorouracil (CMF) drug combination on various aspects of learning and memory. We also examined the effects of CMF on cell proliferation and chromatin remodeling as possible underlying mechanisms to explain...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252305/ https://www.ncbi.nlm.nih.gov/pubmed/22152030 http://dx.doi.org/10.1186/1471-2202-12-124 |