Cargando…

Lower-Order Effects Adjustment in Quantitative Traits Model-Based Multifactor Dimensionality Reduction

Identifying gene-gene interactions or gene-environment interactions in studies of human complex diseases remains a big challenge in genetic epidemiology. An additional challenge, often forgotten, is to account for important lower-order genetic effects. These may hamper the identification of genuine...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahachie John, Jestinah M., Cattaert, Tom, Van Lishout, François, Gusareva, Elena S., Van Steen, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252336/
https://www.ncbi.nlm.nih.gov/pubmed/22242176
http://dx.doi.org/10.1371/journal.pone.0029594