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Construction of permanently inducible miRNA-based expression vectors using site-specific recombinases
BACKGROUND: RNA interference (RNAi) is a conserved gene silencing mechanism mediated by small inhibitory microRNAs (miRNAs). Promoter-driven miRNA expression vectors have emerged as important tools for delivering natural or artificially designed miRNAs to eukaryotic cells and organisms. Such systems...
Autores principales: | Garwick-Coppens, Sara E, Herman, Adam, Harper, Scott Q |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252340/ https://www.ncbi.nlm.nih.gov/pubmed/22087765 http://dx.doi.org/10.1186/1472-6750-11-107 |
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