Deletion of the RNaseIII Enzyme Dicer in Thyroid Follicular Cells Causes Hypothyroidism with Signs of Neoplastic Alterations

Micro-RNAs (miRNAs) are small non-coding RNAs that regulate gene expression, mainly at mRNA post-transcriptional level. Functional maturation of most miRNAs requires processing of the primary transcript by Dicer, an RNaseIII-type enzyme. To date, the importance of miRNA function for normal organogen...

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Detalles Bibliográficos
Autores principales: Rodriguez, Wendy, Jin, Ling, Janssens, Véronique, Pierreux, Christophe, Hick, Anne-Christine, Urizar, Eneko, Costagliola, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252359/
https://www.ncbi.nlm.nih.gov/pubmed/22242190
http://dx.doi.org/10.1371/journal.pone.0029929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252359/
https://www.ncbi.nlm.nih.gov/pubmed/22242190
http://dx.doi.org/10.1371/journal.pone.0029929

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