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1,25-Dihydroxyvitamin D3 Treatment Delays Cellular Aging in Human Mesenchymal Stem Cells while Maintaining Their Multipotent Capacity
1,25-dihydroxyvitamin D3 (1,25D3) was reported to induce premature organismal aging in fibroblast growth factor-23 (Fgf23) and klotho deficient mice, which is of main interest as 1,25D3 supplementation of its precursor cholecalciferol is used in basic osteoporosis treatment. We wanted to know if 1,2...
Autores principales: | Klotz, Barbara, Mentrup, Birgit, Regensburger, Martina, Zeck, Sabine, Schneidereit, Jutta, Schupp, Nicole, Linden, Christian, Merz, Cornelia, Ebert, Regina, Jakob, Franz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252365/ https://www.ncbi.nlm.nih.gov/pubmed/22242193 http://dx.doi.org/10.1371/journal.pone.0029959 |
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