Antibody Inhibition of a Viral Type 1 Interferon Decoy Receptor Cures a Viral Disease by Restoring Interferon Signaling in the Liver

Type 1 interferons (T1-IFNs) play a major role in antiviral defense, but when or how they protect during infections that spread through the lympho-hematogenous route is not known. Orthopoxviruses, including those that produce smallpox and mousepox, spread lympho-hematogenously. They also encode a de...

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Detalles Bibliográficos
Autores principales: Xu, Ren-Huan, Rubio, Daniel, Roscoe, Felicia, Krouse, Tracy E., Truckenmiller, Mary Ellen, Norbury, Christopher C., Hudson, Paul N., Damon, Inger K., Alcamí, Antonio, Sigal, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252373/
https://www.ncbi.nlm.nih.gov/pubmed/22241999
http://dx.doi.org/10.1371/journal.ppat.1002475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252373/
https://www.ncbi.nlm.nih.gov/pubmed/22241999
http://dx.doi.org/10.1371/journal.ppat.1002475

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