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Nuclear Receptor HNF4α Binding Sequences are Widespread in Alu Repeats

BACKGROUND: Alu repeats, which account for ~10% of the human genome, were originally considered to be junk DNA. Recent studies, however, suggest that they may contain transcription factor binding sites and hence possibly play a role in regulating gene expression. RESULTS: Here, we show that binding...

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Detalles Bibliográficos
Autores principales: Bolotin, Eugene, Chellappa, Karthikeyani, Hwang-Verslues, Wendy, Schnabl, Jake M, Yang, Chuhu, Sladek, Frances M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252374/
https://www.ncbi.nlm.nih.gov/pubmed/22085832
http://dx.doi.org/10.1186/1471-2164-12-560