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Ndc10 is a platform for inner kinetochore assembly in budding yeast

Kinetochores link centromeric DNA to spindle microtubules and ensure faithful chromosome segregation during mitosis. In point-centromere yeasts, the CBF3 complex, Skp1:Ctf13:(Cep3)(2):(Ndc10)(2), recognizes a conserved centromeric DNA element through contacts made by Cep3 and Ndc10. We describe here...

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Detalles Bibliográficos
Autores principales: Cho, Uhn-Soo, Harrison, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252399/
https://www.ncbi.nlm.nih.gov/pubmed/22139014
http://dx.doi.org/10.1038/nsmb.2178