A METAL SWITCH FOR CONTROLLING THE ACTIVITY OF MOLECULAR MOTOR PROTEINS

Kinesins are molecular motors that require a divalent metal ion (e.g., Mg(2+)) to convert the energy of ATP hydrolysis into directed force production along microtubules. Here we present the crystal structure of a recombinant kinesin motor domain bound to Mn(2+) and ADP, and report on a serine to cys...

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Detalles Bibliográficos
Autores principales: Cochran, Jared C., Zhao, Yu Cheng, Wilcox, Dean E., Kull, F. Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252401/
https://www.ncbi.nlm.nih.gov/pubmed/22198464
http://dx.doi.org/10.1038/nsmb.2190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252401/
https://www.ncbi.nlm.nih.gov/pubmed/22198464
http://dx.doi.org/10.1038/nsmb.2190

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