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A METAL SWITCH FOR CONTROLLING THE ACTIVITY OF MOLECULAR MOTOR PROTEINS
Kinesins are molecular motors that require a divalent metal ion (e.g., Mg(2+)) to convert the energy of ATP hydrolysis into directed force production along microtubules. Here we present the crystal structure of a recombinant kinesin motor domain bound to Mn(2+) and ADP, and report on a serine to cys...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252401/ https://www.ncbi.nlm.nih.gov/pubmed/22198464 http://dx.doi.org/10.1038/nsmb.2190 |