c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells

Expression of c-Myb is required for normal hematopoiesis and for proliferation of myeloid leukemia blasts and a subset of T cell leukemia but its role in B-cell leukemogenesis is unknown. We tested the role of c-Myb in p190(BCR/ABL)-dependent B-cell leukemia in mice transplanted with p190(BCR/ABL)-t...

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Detalles Bibliográficos
Autores principales: Waldron, Todd, De Dominici, Marco, Soliera, Angela Rachele, Audia, Alessandra, Iacobucci, Ilaria, Lonetti, Annalisa, Martinelli, Giovanni, Zhang, Ying, Martinez, Robert, Hyslop, Terry, Bender, Timothy P., Calabretta, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252490/
https://www.ncbi.nlm.nih.gov/pubmed/21960247
http://dx.doi.org/10.1038/leu.2011.264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252490/
https://www.ncbi.nlm.nih.gov/pubmed/21960247
http://dx.doi.org/10.1038/leu.2011.264

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